Genomics

We study rare founder mutations leading to neurodegeneration using individual and population genetics, functional genomics (single cell transcriptomics, multiomics), and Long Read Sequencing. The emphasis is on the genetics of the Colombian population.

Affiliated Researchers

Kenneth S. Kosik

Principal Investigator
Exploration of fundamental biological processes, particularly those related to the brain and its evolution.
Stem Cells and Neurodevelopment
Cellular Neurobiology and Pathobiology
Genomics
Neurophysiology

Juliana Acosta-Uribe

Assistant Researcher
Leading genetic analyses of Latin-American cohorts with ADRD and exploring the demographic influence on the genesis of such illnesses
Genomics

Sarah Eger

Graduate Student Researcher
Studying the functional genomics of Alzheimer’s Disease, using single cell transcriptomics and next-generation and long-read genome sequencing.
Genomics

Christian Bustamante

Graduate Student Researcher
Studying malfunctions in neural circuit activity that result in disease and mental illness, in order to develop appropriate treatments.
Neurophysiology

Collaborators

  • J. Nicholas Cochran (HudsonAlpha Institute for Biotechnology)
  • David Aguillon, Grupo de Neurociencias de Antioquia, (University of Antioquia, Colombia)
  • Diana Matallana, Javariana, Colombia